Giloba 60

Description

Indications
Primary uses-
Cerebral insufficiency: memory deficit, depression, attention and memory loss that occur with Alzheimer’s disease and multi-infarct dementia.
Vertigo and tinnitus (ringing in the ear) of vascular and involutional origin Peripheral vascular disease: improvement of pain-free walking distance in
Peripheral Arterial Occlusive Disease in Stage II according to Fontaine (intermittent claudication) in a regimen of physical therapeutic measures, in particular walking exercise.
Other potential use-
Protective action in hypoxia
Acute cochlear deafness
Sexual dysfunction associated with SSRI use
Therapeutic Class
Herbal and Nutraceuticals
Description
Ginkgo is generally accepted as a remedy for minor deficits in brain function, such as those that occur with advancing age. It is used to improve concentration and combat short-term memory loss due to clogged arteries in the brain, and to treat dizziness, ringing in the ears, headache, and emotional hypersensitivity accompanied by anxiety.
Pharmacology
Ginkgo biloba is one of the most widely used and studied herbal products around the world. The leaves are generally used to make medicine. Ginkgo biloba leaf extract mainly contains Ginkgo flavone glycosides and terpene lactones. Most Ginkgo supplements are standardized to 24% of the Ginkgo flavone glycosides and 6% of the terpene lactones. The Ginkgo leaf extract protects the neurons from oxidative damage potentially preventing the progression of tissue degeneration in patients with dementia. Additionally, Ginkgo biloba leaf extract improves blood flow throughout the body, and it restores the balance between prostacyclin and thromboxane A2 resulting in improved vasoregulation. Vascular contraction and improvement in the venous tone are thought to be the result of phosphodiesterase inhibition and release of catecholamines.
Dosage & Administration
For adults: 120-240 mg/day. 1 or 2 capsule 2 to 3 times daily or as advised by the physician.
Contraindications
Ginkgo should only be used with caution in patients taking anticoagulant or antiplatelet agents i.e. warfarin, heparin & aspirin. It is also contraindicated in bleeding disorders due to increased bleeding potential associated with chronic use (6-12 months) or before elective surgery. Contraindicated in patients with known risk factors for intracranial hemorrhage. There is no known restriction of the use of ginkgo in pregnancy and lactation.
Side Effects
No side effects following proper administration of designated therapeutic dosages. In pooled clinical trials involving 10,000 patients, the incidence of side effects produced by ginkgo extract was extremely small. There were few cases of headaches, dizziness, palpitation, gastrointestinal disturbances, bleeding disorders & skin hypersensitivity reactions. Rare cases of stomach or intestinal upsets, headaches, or allergic skin reactions have been documented. In higher than recommended doses, diarrhea, nausea, vomiting, restlessness, and weakness may occur.
Pregnancy & Lactation
Ginkgo biloba is not recommended for use during pregnancy. It is not known whether this product passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this product is not recommended. This drug is also not recommended for use in children
Precautions & Warnings
Before taking this product, tell your doctor if you are allergic to it, have bleeding problems, seizures, convulsions or epilepsy. Ginkgo biloba may decrease the ability of blood to clot. Stop taking this product at least 2 weeks before surgery
Storage Conditions
Ginkgo Biloba Capsule should be stored at room temperature. Protect from moisture and light.